Not encouraging you or anyone to take Ozempic but the fact that they work so well for weight loss proves that there is a biological pathway that reinforces overeating. It’s beyond the dopamine feedback loop - there is an actual biochemical reason that we are compelled to overeat. It validates the idea that being successful at weight management isn’t decided by willpower alone. Some people are just more biochemically predisposed to overeat.

These new GLP-1 receptor agonists have shown promise mitigating many compulsive behaviors from overeating to alcoholism to behavioral compulsions. It’s a new area of pharmacology and I’m super excited to watch them discover novel treatments for all manners of issues.