I have just recently reinstalled and remodded skyrim with MO2! I chose MO2 specifically because it has a linux version which I downloaded off the github.

I have found that MO2 has a lot of functionality built in that just isn't well explained in the tutorial. and it can be quite daunting to start.

For one, you don't have to worry about skse. it comes with that when you choose Skyrim as the instance of MO2 you want to make. MO2 will then launch every time you launch Skyrim. And once it launches, you have all the options!

From MO2, you can choose to run different versions of skyrim. it can run the vanilla PC launcher for you if you want to manually set your graphics settings.

It can launch directly with SKSE, which is what you'll need for most mods. (if you're playing modded skyrim, you'll likely be launching from here most times unless there's specific settings in the basic launcher you want to change)

It also comes with LOOT (which is a load order optimizer) already preinstalled. You just have to click the button to have it sort your load order for you. The load order is usually decent enough for most modlists (depending on size) but there are many guides to load orders for skyrim if you're interested in changing things around to be better optimized for your needs.

my advice is honestly sit down and take some time to kinda go over where everything is. Before MO2 I was a vortex person. I am considering never going back.

if you have any specific questions, I can maybe try to help.