I think not having neighbours is only really possible for a small number of people, mostly in agricultural work. If the majority of people didn't want neighbours, we could not sustain the populations that exist, end of story.

Spreading people out is part of the reason why so many counties in the US are going broke, because infrastructure per person gets so much more expensive when compared to property taxes.

Cars are certainly needed in rural areas, but emphasis on the rural. Even modest towns could and can afford small public transport networks if they plan correctly.