It's possible, but it can really change the type of games available to you too. I used to love Skyrim and similar, but eventually found I needed a minimum session of 2-3 hrs, otherwise I hadn't even done any real playing, just inventory management, or getting crafting supplies. These days, with kids and work, I like rally simulator games, it can be satisfying to just do one or two stages, which can take as little as 5-20 mins. But it's a whole different thing, no story, character development, surprises...a bit like going from watching Kurosawa films to watching the sports highlights.