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I didn't like SSRIs. I found the effects for me to be very, very marginal, and the side effects--weight gain, sexual dysfunction--to be very unpleasant. The Zyprexa I was given (an atypical antipsychotic, I believe) was even worse for weight gain and sexual dysfunction. I preferred bupropion, which had neither side effect. The effects were still very marginal, IMO.
A lot of people have a REALLY hard time getting off SSRIs if they it doesn't work, if the side effects are too serious, etc. Some people report 'brain zaps', and serious withdrawal. Like, really bad. It can take months for the withdrawal symptoms to ease or go away completely.
If it's for depression, I'd look into TCMS. It's probably more expensive up front, but supposedly you can have significant improvement in 50 or fewer sessions.