I have. I have it on a laptop and will probably put it on my desktop (waffling between Bazzite and Arch). It's great, and it's one of the easiest setups I've had to get going with gaming. I recommend joining their Discord, too.

The only thing that is currently a problem, that may be a non-issue when bootc has a full release, is installing certain VPN clients. If it exists as a flatpak, RPM, or in fedora repos, should be fine. If it installs by copying various files around and making system changes on demand at runtime (like Private Internet Access), doesn't currently work.