From what I've seen in desert west, unless you're hot or the person sitting next to you is trying to peddle something or just has a very loose filter, strangers are far more likely to chat up the bus driver.
The most interaction I've seen is when a group of Mormons started a cringey debate with a group of Mennonites on the train. Everyone else around them very intentionally put on their headphones or stared out the window.