Japanese researchers got obese mice to lose weight using single-shot gene editing to get their bodies to produce the same drug that is in Ozempic. (www.nature.com)

submitted 1 day ago by Lugh@futurology.today to c/futurology@futurology.today

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[-] Lugh@futurology.today 14 points 1 day ago

Although gene editing techniques are patentable in some countries, I wonder if this could be much cheaper than the monthly weight loss shots, which can be very expensive in some countries.

In the future will medical tourism for gene editing be a thing? Maybe the same clinics that offer hair restoration, botox and plastic surgery today will have it as an option.

[-] Alaik@lemmy.zip 3 points 1 day ago

Gene editing treatments in general are prohibitively expensive (At least in the US). Casgevy cures sickle cell and beta-thallasemia but I want to say it costs $300,000? For the one dose.

You'd think insurance would jump on that given how much ER visits are, and the prevalence of ER visits in that patient demographic though.

[+] metaStatic@kbin.earth -12 points 1 day ago

Humans will do absolutely anything but eat properly

[-] CanadianCarl@sh.itjust.works 2 points 12 hours ago* (last edited 12 hours ago)

https://youtu.be/Tj_D-Ed-s-Y https://youtu.be/eLWI1EKfMs4

[-] apotheotic@beehaw.org 23 points 1 day ago

Dude fuck this attitude. I've been trying to eat properly for actual years. I try to eat fewer carbs, I count my calories, and do my damnedest to stay in a caloric deficit. I work out frequently and hydrate well. I take a probiotic to ensure my gut microbiome is going to be on its best behaviour.

And then my body screams at me that I am hungry. And on the first day of this, I can mind over matter. On the second day, it is more difficult, but I can just about keep it up. On the nth day it makes me feel sick with how hungry my body is telling me I am. I eat, and I go over calorie budget. My mindset spirals. I end up 3 weeks down the line and my weight is right back where it started.

I want to make the change. I'm fucking trying. It is not as simple as people "doing absolutely anything but eating properly".

[-] Cort@lemmy.world 10 points 1 day ago

And all that doesn't even touch on modern producers purposely designing their food products to be literally addictive.

[-] Demdaru@lemmy.world -3 points 1 day ago

First of all, damn.

Second of all, try drinking water whenever hungry, or chewing gum. It may help. You already got so far, I even slightly jealous ^^'

[+] metaStatic@kbin.earth -11 points 1 day ago

you're being sabotaged by a century of misinformation and food science designed to make you buy more. you end up feeling hungry because you're not getting what you need from whatever you're eating. The calories don't mean shit, you're not a combustion engine, you need nutrients and the rest literally takes care of itself.

A low carb whole food diet would be more than enough to see vast improvements but if you can get 30 days of carnivore under your belt your joints will tell you immediately if what you just ate was really food.

the goal is to be healthy and being a healthy weight is just a side effect.

[-] apotheotic@beehaw.org 8 points 1 day ago

That's all fine and dandy, but your original comment is still a shocking oversimplification of a really not simple issue.

[-] metaStatic@kbin.earth -4 points 16 hours ago

illness isn't caused by a lack of medication ... it really is as simple as stop doing the thing that harms you.

[-] apotheotic@beehaw.org 4 points 15 hours ago

It really, truthfully, is not. I never once said that a lack of medication is the thing stopping me from losing weight, so idk why you're bringing that up, but "just stop eating in an unhealthy way" is a simple sentence but far more complex in practice.

However, we clearly don't see eye to eye on this so I'm just going to disengage.

[-] Safeguard@beehaw.org 4 points 1 day ago

It's not that simple.

Good food is expensive and sometimes it looks like good food but still is full of all kinds of shit. Hunger generating chemicals making you eat more for instance.

I'd love for the FDA to start actually giving a damn instead of people having to be pay to get fat and then pay to get thin.

[-] Kowowow@lemmy.ca 2 points 1 day ago

The problem is in the moment it can seem like you are doing alright, I almost went and got a slushie with icecream mixed in after I had forgotten I already had a bowl of icecream

this post was submitted on 16 Jul 2025

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