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This might be the dumbest thing I've asked out loud. But I'm really interested in how the measles virus causes immune system amnesia, and if that specific aspect of the measles virus might be able to treat autoimmune disorders.

obviously, this has the drawback that the patients would be infected with measles. but would their immune system stop attacking their own body?

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[-] roofuskit@lemmy.world 4 points 2 months ago* (last edited 2 months ago)

As someone with Lupus, you're misunderstanding these things entirely. Have you considered becoming the head of the HHS is the US?

Also this is a question, so it's not dumb.

[-] givesomefucks@lemmy.world 1 points 2 months ago

Autoimmune disorders cause the immune system to not recognize anything. They can't tell friend from foe, and default to attacking everything.

Measles causing immune system amnesia by attacking and killing where the immune system stores memories.

The immune system still attacks everything, it just doesn't remember what works on every virus.

So it will still attack friendly parts of your body, because it's "targeting system" still just tells it to blast everything that moves.

And because it doesn't remember how to fight actual threats, it generated a larger and less effective immune response, then all those immune cells attack random stuff, which leads to measles making any autoimmune issue even worse.

[-] MysteriousSophon21@lemmy.world 2 points 1 month ago

That's not quite right - autoimmune disorders don't attack "everything" indiscriminately, they target specific self-antigens (like myelin in MS or joint tissue in RA) while still functioning normally against most pathogens.

this post was submitted on 07 Aug 2025
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