What's the thing between the PSU and the GPU?
And what's the orientation of the fans?
The main question is: does your GPU have a no fan idle mode? AFAIK the fans won't spin till the GPU reaches 60°C and cool it back down to 40 or 45, sorry can't remember.
Usually you want to have a 3 intake at the front panel and 2 exhausts, one at the back inline with the CPU cooler and one at the top as far behind as possible. Since you're running, what looks like, a mini tower you can with the same layout as a midi but 2+2 (2 intake front, 1 exhaust back, 1 exhaust top far behind). For a positive pressure you can mount an additional fan on top, at the front as an intake.
For the best result you should take your time and fiddle around, measure and document