I found this chart on reddit some time ago, I thought to repost it here as well
Needs a column for "makes you feel like you are Being John Malkoviching as you linger behind your own eyes and watch another version of yourself interact with the world while being confused about who is actually controlling your vessel", and put Bupropion at a 12.
That... explains a lot about a few months of my life
That shit is trippy as fuck to me, and not in a good way. More of a Twilight Zone sorta way.
I took Bupropion exactly once, and that day happened to coincide with the day of a first date. There was not a second date. I'd say something to her, but it wasn't me, it was the "me" who was standing about three feet in front of me. I swear to Cotton Eyed Joe I could see the back of my own fucking head.
I didn't get it nearly that acutely, but I made several stereotypical "crazy person sketches" of my view through my glasses with all the visible objects being written words instead of objects, trying to convey how lifeless and disconnected I felt from my own sensory input
a few years later I learned that's called "dissociation" and it's not supposed to happen 🫠
I have never been diagnosed with anything and never consumed any antidepressant or other psychopharmaceutical, but I get what you are describing like a lot, especially lately but since practically forever, at least since I was 12.
I practically often feel like the 2 taxi drivers in the Hudsucker Proxy (as I identify 2 internal voices) describing, in a detached way, whatever I do, including me typing on the keyboard right now (with one of them making fun of the fact that I still haven't got the confidence to never look at the keys while typing).
Are we talking here about something that would hinder me functioning socially and professionally or does what I described count towards something I should take care of?
Yeah, that would be something to see a professional about, I think.
Where is a living wage? That shit really helped me.
I'm glad Buproprion has few side effects from this chart.
However, for those considering it, here's some missing side effects:
I'm not saying these are pros or cons. Each person should assess how these side effects will affect their own situation.
I suffer from persistent depressive disorder with occasional major depressive episodes (aka "double depression"). These are just some notes in case anyone can relate. I also just find this kind of thing interesting...
Had a doctor tell me I should never feel the antidepressant. Should be a background thing. Thought that was good advice.
Setraline leveled me the fuck out.
It's kinda funny how much medicines' effects can vary from person to person, I tried sertraline and had absolutely no difference, whereas my mother and my sister take it and it works for them
May I ask, what do you mean it leveled you out?
Anger flare ups stemming from depression. Took cognitive behavioral therapy for a time until I could learn the coping skills. Still take the setraline.
Have noticed when I wheen off/am off it am more prone to those flare ups. They don't happen outright, I just notice them more prominently.
Seems to be missing the entire MAOI class (moclobemide, selegiline, phenelzine, tranylcypromine, isocarboxazid), and most tricyclics (clomipramine, imipramine, nortriptyline, et al)
I did a bit of searching but I don't really understand what QTc prolongation is. Can anyone help me understand?
During your heart’s electrical conduction there are different phases. You have the contraction of the atria. The little pumps above the ventricle (main pumps) whose role is to help fill up the ventricles. The contraction of the ventricles. The main pumping part of your heart that pumps the blood to both your body and your lungs. And the repolarisation of both the atria and the ventricles. Basically the heart muscle reseting for another beat.
The atria contract first and repolarise first. On an ECG (heart trace) the atrial contraction corresponds to the P-wave. The little wave at the front. The atrial repolarisation occurs during ventricular contraction so you can see it on the ecg. When the ventricular contraction occurs you see the sharp up and down squiggles on the ECG. This is the QRS complex. Following ventricular contraction there is ventricular repolarisation. This occurs after the QRS complex and looks like a really big P-wave. This is the T-wave.
QTc prolongation is when the T wave takes a long time to occur after the QRS complex. When it gets too bad it is dangerous because the electrical energy that occurs in the T wave can set off another contraction of the heart. This contraction occurs outside of the normal pattern of the heart and the heart does not pump effectively leading to something called torsades de pointe which can develop into ventricular fibrillation leading to cardiac arrest (your heart not really pumping any blood).
Here is a labeled picture of an ECG ignore the u-wave its not really relevant and does not always occur.
Here is a picture of the heart showing the location of the atria and ventricular Heart
Thank you, that's really helpful
https://en.m.wikipedia.org/wiki/QT_interval
The QT interval is a measurement made on an electrocardiogram used to assess some of the electrical properties of the heart. (...) An abnormally long or abnormally short QT interval is associated with an increased risk of developing abnormal heart rhythms and sudden cardiac death.
QTc stands for QT corrected for heart rate, the medication that increases QTc will increase the risk of certain dangerous heart conditions.
Thank you 😊
Pretty strange considering fluoxetine makes me sleep waayyy too much
There's no section for "brain zaps".
Escitalopram and Trazodone here. Out like a light on the latter. Only way I can function.
I tried many of those with no success, until tried Duloxetine and the response was optimal. Each persons has different reactions.
If y'all have had really bad side-effects look into pharmacogenomic testing, it can help rule out bad medicines before you try them
I had one done a while ago and it marked a ton of medicines that I had already tried, (and had bad effects from) and a bunch I hadn't tried yet. Since then, I've had much fewer bad experiences
notes
the one I did had a specific brand name but I don't remember what it was. (It was a while ago) I'm pretty sure this is what it was though
you might have to remind your doctor about it when they're prescribing medications, this still isn't very well known afaik
this isn't sponsored/paid/other bullshit, this is an actual recommendation (though I felt like one of those 'ask your doctor if !@#$ is right for you' american commercials the entire time writing it)
Antidepressants get such a bad rep, they're truly amazing
Can confirm, bupropion causes insomnia.
I sometimes have to take nighttime benadryl to help me sleep.
Been on it consistently for over a decade now and have always been funky with sleep. I started back in undergrad when the pressure of life left me spiralling out of control, and have since always thought I was just a weird sleeper.
I have insomnia semi often, usually anxiety-induced, but I've never thought that it could be the bupropion directly.
Very curious, and good to know.
So I have never had depression but I am aware that Sertraline is probably the most common. Is there some higher rate of effectiveness it has over the less alternatives with less side effects? Is it just that it's cheaper?
Research, and more anecdotal than I can count, including a number of my own, shows psilicybin (I use ground magic mushrooms) at slightly-less-than ‘feel high’ doses 4 days a week (aka micro or threshold dose) equals, or surpasses efficacy of any of that list.
No side effects.
Shit works, and you don’t have to “get high” and lose your moral compass, etc.
If you abuse psilicybin, it just stops working. You really can’t get addicted to it at all. Also there is NO ‘lethal dose’. You can’t die from it.
Fuck Rx!
Now I know y I dont have that much of a Craving for Sex anymore. Thought I just got old.
Can you orgasm? Anorgasmia is a common effect.
Yes I Can. Otherwise I guess id just never have Sex
Lucky. Citalopram would cause me to create friction burns because I couldn't cum. It was awful.
Tried a bunch of them, none really worked except for Venlafaxine. Had sexual dysfunktion which was an unacceptable side effect for me so I also quit them. This sucks.
Venlafaxine almost killed me which is fun :^)
Same here. Wasn't funny at all.
An off label use for Trazadone is as a sleep aid. At doses under 150 mg it doesn't really work as an antidepressant but will make you drowsy. I've been prescribed it before as the first step before Ambien
Amitriptyline as well, started taking it for peripheral neuropathy. Ended up on a higher dose because it's a heavy sedative. Take it before bed, and I'm out. I was taking Zopiclone before, to help me sleep but don't need it now. Also it failed as an antidepressant but works wonders for antianxiety.
This is a safe place to discuss, vent, support, and share information about mental health, illness, and wellness.
Thank you for being here. We appreciate who you are today. Please show respect and empathy when making or replying to posts.
If you need someone to talk to, @therapygary@lemmy.blahaj.zone has kindly given his signal username to talk to: TherapyGary13.12
The rules for posting and commenting, besides the rules defined here for lemmy.world, are as follows:
If BRIEF mention of these topics is an important part of your post, please flag your post as NSFW and include a (trigger warning: suicide, self-harm, death, etc.)in the title so that other readers who may feel triggered can avoid it. Please also include a trigger warning on all comments mentioning these topics in a post that was not already tagged as such.
To partner with our community and be included here, you are free to message the current moderators or comment on our pinned post.
Some moderators are mental health professionals and some are not. All are carefully selected by the moderation team and will be actively monitoring posts and comments. If you are interested in joining the team, you can send a message to @fxomt@lemmy.dbzer0.com.
