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submitted 3 weeks ago by Redditsux@lemmy.world to c/world@lemmy.world
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[-] Nougat@fedia.io 152 points 3 weeks ago
[-] IphtashuFitz@lemmy.world 121 points 3 weeks ago

Latest FDA guidance: Take vitamin A, wash it down with raw milk, and attend virus spreading parties to build natural immunity.

[-] Nougat@fedia.io 22 points 3 weeks ago

That last part actually works by culling the people who have the most severe symptoms. So you would be building natural immunity in the population, over a long period of time, by dying before you produce offspring.

[-] shininghero@pawb.social 23 points 3 weeks ago

Only for more genetically stable diseases that don't mutate into new strains every single year.

[-] Nougat@fedia.io 11 points 3 weeks ago

Guess we'll just have to cull the herd every year then.

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[-] partial_accumen@lemmy.world 35 points 3 weeks ago

FDA approval in never.

I'm not even bothering with FDA recommendations anymore with Kennedy in charge. I'll be reading the Canada Health and NHS (UK) notices. If it means crossing a national border to get a vaccine, I'm onboard.

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[-] Treczoks@lemmy.world 7 points 3 weeks ago

Theoretically, this could approved in Europe, which is fine for me. But I doubt the pharmaceutical industry will let a working, permanent immunisation against the common cold happen. That would mean billions and trillions of lost business.

[-] Supervisor194@lemmy.world 15 points 3 weeks ago

I never understand it when this argument is made. It assumes that there aren't entities out there making $0 on the common cold that would refuse to take the absolute fucking windfall that would be generated if such an immunization were to be brought to the market.

Like "oh, you know, we'd like to make this immunization and make billions of dollars ourselves but these OTHER guys are already making billions of dollars and we sure wouldn't want to step on their toes."

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[-] Lemmyoutofhere@lemmy.ca 7 points 3 weeks ago

Hard for them to approve it if there is no FDA.

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[-] ThePantser@sh.itjust.works 109 points 3 weeks ago

Keep me updated on which countries approve its use so I can add them to my travel plans.

[-] HarkMahlberg@kbin.earth 42 points 3 weeks ago

Might be a great excuse to visit Denmark... I hear it's wonderful there.

[-] frank@sopuli.xyz 30 points 3 weeks ago

It is. Come visit (but like be respectful please it's nice)

  • source: live here
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[-] dzso@lemmy.world 9 points 3 weeks ago

Make sure they're also countries that will give vaccines to foreigners. I had a hell of a time getting routine flu shots in Spain, Hungary and Thailand. The systems are often set up with the assumption that you're a citizen or have a national healthcare ID of some sort. Without that, good luck finding a clinic who will give you a shot.

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[-] turtle@lemm.ee 107 points 3 weeks ago

Now consider that Scripps Research, who is developing this, is US-based and receives a lot of federal government funding, and that Trump/Musk/DOGE have been slashing and burning all kinds of federal science staffing and funding. Also consider that their main federal funding comes from HHS, which RFK Jr., notorious vaccine hater, heads.

Then weep. Progress on this may be stalled for a long time.

[-] tempest@lemmy.ca 25 points 3 weeks ago

Maybe, or maybe some other country poaches them.

[-] turtle@lemm.ee 8 points 3 weeks ago

True, that could also happen, but I wonder how transferable this type of research project is. Does the research lead actually own it and can take it with him or her to a new place, or does Scripps own it? I don't know the answer.

[-] jaggedrobotpubes@lemmy.world 11 points 3 weeks ago

File --> export

[-] eric5949@lemmy.world 88 points 3 weeks ago

No way they'll let Americans have it

[-] Yawweee877h444@lemmy.world 38 points 3 weeks ago

Think about all the capitalist profit businesses make for common cold symptoms alone, with over the counter meds and stuff.

No way something like this would be allowed in our current society.

[-] SelfHigh5@lemmy.world 26 points 3 weeks ago

Just an interesting thing to share… I lived in the US until I was 40 and moved to Norway. They just don’t sell “cold remedy” meds here, or at least not even close to the extent the US does. We have sore throat drops, and OTC pain relief. Some cough medicine but it’s pretty weak imo. I suspect this is because the expectation here is that if you’re sick, you take sick time off work. You can rest and recover. Going to the doc to get sick time approved is at most like $20 and if you and your doc have a good relationship, you can do this via email. In the US, you're expected to power through unless contagious and even then, just try to pretend you’re okay.

[-] Yawweee877h444@lemmy.world 17 points 3 weeks ago

What you're saying hits home.

Conservatives have this tough guy routine, that going to work when you're sick is just manly or "alpha". It's bullshit. Then they spread it so everyone else can get it.

But the tough thing to do, is go to work, after pumping yourself full of nyquil, or Tylenol, or whatever. It's just so stupid and obvious. They're so "tough" yet they need all this OTC junk to ease the symptoms. Not to mention, not being productive at work, cause you feel like shit. As well as taking longer to get better.

Personally, I prefer not to take any meds at all. Just go home, sleep a lot, drink water, eat soup, chill, rest, etc.

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[-] samus12345@lemm.ee 5 points 3 weeks ago* (last edited 3 weeks ago)

I just got over being sick for 2 weeks and even though I was lucky enough to have that much sick time, I absolutely wanted the strongest meds I could get because I was miserable.

you’re expected to power through unless contagious

No, you're expected to power through and they don't give a fuck whether you're contagious or not.

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[-] sheridan@lemmy.world 9 points 3 weeks ago* (last edited 3 weeks ago)

However, I'd expect businesses would also want to reduce cold and covid's impact on employee productivity? Wouldn't fewer employees needing to take sick time because of cold/covid increase their profits? Outside of businesses that profit from cold/covid, I don't see what the motivation for businesses would be against this vaccination.

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[-] orbituary@lemmy.dbzer0.com 20 points 3 weeks ago

Vaccine tourism will become a thing.

[-] pivot_root@lemmy.world 6 points 3 weeks ago

Knowing the current administration, it will end up just like abortion tourism... but instead of only being persecuted in red states, it will be federally outlawed.

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[-] Buelldozer@lemmy.today 7 points 3 weeks ago

No FDA means no one to stop it! 😂

[-] eric5949@lemmy.world 5 points 3 weeks ago

We'll have an fda, once they rip it to sheds they'll stock it with whoever they want to and then say look we fixed the fraud, listen to these guys now. Having a government agency that can say "no drug that competes with an oligarchs drug you can't be approved" or "yes, you can shove unproven computer tech into people brains" is far to powerful to throw completely away.

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[-] NJSpradlin@lemmy.world 6 points 3 weeks ago

Is this annually or once and done? I may just go over seas if it’s a one-time deal.

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[-] Cocopanda@futurology.today 30 points 3 weeks ago

After the most recent flu or cold I had. I would do anything for a cold vaccine. Flu shot likely kept me safe from that last bug I had. But still would like a cold vaccine to.

[-] volvoxvsmarla@lemm.ee 14 points 3 weeks ago

About a month ago I had the flu - the real flu - for the first time either in ages, or in my life, and I actually had gotten vaccinated in autumn, and man, I thought I was dying. For two weeks I couldn't do anything. Just looking at the stairs gave me endocarditis. I never run fevers and I was just popping painkillers to keep it under 40 degrees. That was nuts. So during and afterwards I mostly been thinking about three things: 1. I would have died for real if I didn't have some basic protection from the vaccine, 2. I want a vaccine against the common cold as well, and 3. Jesus Christ please I don't want to die from a stupid cold or flu, at least make it Covid, but that's such a lowball way to go

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[-] shittydwarf@lemmy.dbzer0.com 30 points 3 weeks ago
[-] avidamoeba@lemmy.ca 24 points 3 weeks ago* (last edited 3 weeks ago)

OK, so if I understand this correctly, they don't train the immune system to target these sugars, since they're used by human cells. Instead, they remove them during the vaccine administration so the immune system can train on the bare spike protein. Cool. Now how would this help when new virus copies come in with sugar-coated proteins, some time after the sugar stripping agent is gone from the system?

[-] Atelopus-zeteki@fedia.io 25 points 3 weeks ago

What they've found, from the article, and abstract (alas I didn't see any links to full text paper, which may come available after the ACS Spring 2025 meeting), is that they indeed do get an effective broad based immune response against coronaviruses. The 'sugar stripping agent' process is used in the production of the immunogen (basically a glycan stripped version of the more highly conserved spike protein that occurs in all/ many/ a lot of coronaviruses, i.e. which cause common cold, MERS, and COVID19), such that a broad based immune response is evoked when applying it, some time after the sugars (glycans) have already been stripped. Remember the spike is the consistent (conserved) part, and the glycans are the camouflage bits. Researchers have been trying to come up with something based on the spike protein for some time, and this is the sort of breakthrough that they've been working towards. Doubtless more info will be available after the research has been officially presented, March 23-27. (https://www.acs.org/meetings/acs-meetings/spring.html) So it's literally happening now. And may show up on Chi-Huey Wong's google scholar page (https://scholar.google.com/citations?user=GQLirSoAAAAJ) or at Scripps/Sinica (https://www.genomics.sinica.edu.tw/chihueywong/)

[-] meowmeowbeanz@sopuli.xyz 6 points 3 weeks ago

Finally, someone speaking actual biology instead of paranoid rants. Impressive grasp of glycosylation and conserved epitope exposure - you've clearly done your reading beyond headlines. The sugar-stripping approach is ingenious precisely because it targets what viruses try to hide. Current research trajectory looks promising but I'll wait for peer-reviewed publications after that ACS meeting before joining the hype train.

🐱🐱🐱🐱🐱

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[-] AlolanYoda@mander.xyz 8 points 3 weeks ago* (last edited 3 weeks ago)

Yeah I also don't understand this part. Can the antibodies targeting the bare spike protein attach to it despite the presence of the sugars? Or are there a few spike proteins in the virus which do not have the sugars, not enough to effectively develop antibodies but enough for already existing antibodies to attach to?

I may have missed it in the article, I'm not in life sciences so I don't have all the prerequisite knowledge for this

Edit: this came out sounding super negative, I'm actually super excited about this development and all I want is to understand a bit better how it works

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[-] dryfter@lemm.ee 24 points 3 weeks ago

Meanwhile, in the U.S. I'm sitting here wondering if we'll even have a flu shot available for next winter, let alone a new vaccine that can protect from Covid and the common cold.

[-] ABetterTomorrow@lemm.ee 16 points 3 weeks ago

I wonder how this could help those with long COVID.

[-] Redditsux@lemmy.world 13 points 3 weeks ago

I don't think it's going to help them. long covid is past the stage of virus infection. It's where the body is attacking itself.

[-] Natanael@infosec.pub 10 points 3 weeks ago

It depends! Sometimes it's autoimmune, sometimes it's lingering virus, sometimes it's disrupted regulatory systems, etc. When it's the immune system or lingering virus, a new vaccine can often get the immune system to relearn how to correctly handle the virus

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[-] Ledericas@lemm.ee 12 points 3 weeks ago* (last edited 3 weeks ago)

long covid, aka sequelae (medical term) means you had a long last complication that seperate from the virus. the inflammation couldve damaged parts of your body you are chronically suffering from. it might not help, since its not caused by the virus anymore.

its basically like having PHN, or nerve damage after shingles, the vaccine wont help you with that.

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[-] 24_at_the_withers@lemmy.world 9 points 3 weeks ago

Many long COVID infections are causing/caused significant damage to organs (https://pmc.ncbi.nlm.nih.gov/articles/PMC11834749/). A vaccination isn't going to reverse organ damage.

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this post was submitted on 25 Mar 2025
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