Amanda Marcotte remembers that but I don't see examples in her link https://www.salon.com/2025/02/24/what-elon-musks-on-workers-owes-to-gamergate/ It looks like the Wikipedia page was written by someone who noticed the slur on Twitter in 2018 or later, and its focused on the meme graphic not the slur "you are just a mindless machine that exists for my pleasure or as an obstacle to overcome." I think Marcotte served in the Internet Feminism Wars on the feminist side.
The reporting on Gamergate that I can find focuses on the death threats and doxing not insults but "NPC" sounds like the kind of slur that the anti-feminists would have used.
Good point that SlateScott commented on accusations of abuse in rationalist and adjacent organizations. Would the Goldwater Rule have applied? At least there has been some reporting on those accusations but I don't know if it was on the ground or just phoning and emailing people from NYC, Chicago, or LA.
Someone with biochem, pharmacy, or psychology training could comment on some things SlateScott has written.