[-] N0t_5ure@lemmy.world -5 points 1 day ago

I will say that you don't have to lie down and take it. Over the past few years I've been on a journey to restore and rejuvenate my body, and the results have been miraculous. I went from morbidly obese with metabolic syndrome, including uncontrolled high blood pressure, to literally the best physical condition of my life. 60 year old me could kick 30 year old me's ass any day of the week. All of my health issues have been resolved, and all of my old man aches and pains have gone away. I did a deep dive on the state of the art of longevity science, which is reasonably summarized in Peter Attia's book Outlive. (It's a free audiobook on spotify premium.) I've basically optimized sleep, exercise, nutrition, supplements, and the use of prescription drugs, including the drug rapamycin. Rapamycin has extended lifespan of every organism it's been tested in, including budding yeast, fruit flies, mice, rats, and non-human primates. While there are ethical and time considerations that make such placebo controlled lifespan studies in humans difficult, there is data to suggest that rapamycin has a similar therapeutic effect in humans. Joan Mannick's 2014 study using Everolimus, a slightly tweaked analog of rapamycin, demonstrated that pulsed mTOR suppression in elderly humans greatly ameliorated immunosenescence, the decline in immune function during aging, and the ongoing trials of rapamycin with respect to ovarian aging have shown impressive effects. I've been on rapamycin for almost 3 years now, and while I can't isolate its effects from my other interventions, I'm pretty much never sick and I've had significant grey hair reversal, which was unexpected. TLDR: there is a lot you can to mitigate the effects of aging and implement "graceful degradation" in your life.

[-] N0t_5ure@lemmy.world 69 points 1 day ago

I turn 60 in June. I'm doing this with my body.

22
[-] N0t_5ure@lemmy.world 88 points 1 week ago

As part of the plan, the US has in principle agreed to lift all primary and secondary sanctions against Iran and to withdraw US combat forces from all bases in the region, the council said according to state media.

The council also said the US has recognized its continued control over the Strait of Hormuz. The council said controlled passage through the waterway would be carried out “in coordination with Iran’s armed forces,” according to the statement reported by state media.

So basically, the U.S. spent a shitload of money bombing Iran so that it could lift sanctions on Iran and leave them with a stranglehold over 20% of the worlds oil supply. Typical Trump "win".

2
Remember, no math! (www.youtube.com)
1
submitted 3 months ago by N0t_5ure@lemmy.world to c/music@lemmy.world
[-] N0t_5ure@lemmy.world 89 points 3 months ago

This makes me want to call it slop even more.

[-] N0t_5ure@lemmy.world 87 points 3 months ago

“If," ["the management consultant"] said tersely, “we could for a moment move on to the subject of fiscal policy. . .” “Fiscal policy!" whooped Ford Prefect. “Fiscal policy!" The management consultant gave him a look that only a lungfish could have copied. “Fiscal policy. . .” he repeated, “that is what I said.” “How can you have money,” demanded Ford, “if none of you actually produces anything? It doesn't grow on trees you know.” “If you would allow me to continue.. .” Ford nodded dejectedly. “Thank you. Since we decided a few weeks ago to adopt the leaf as legal tender, we have, of course, all become immensely rich.” Ford stared in disbelief at the crowd who were murmuring appreciatively at this and greedily fingering the wads of leaves with which their track suits were stuffed. “But we have also,” continued the management consultant, “run into a small inflation problem on account of the high level of leaf availability, which means that, I gather, the current going rate has something like three deciduous forests buying one ship’s peanut." Murmurs of alarm came from the crowd. The management consultant waved them down. “So in order to obviate this problem,” he continued, “and effectively revalue the leaf, we are about to embark on a massive defoliation campaign, and. . .er, burn down all the forests. I think you'll all agree that's a sensible move under the circumstances." The crowd seemed a little uncertain about this for a second or two until someone pointed out how much this would increase the value of the leaves in their pockets whereupon they let out whoops of delight and gave the management consultant a standing ovation. The accountants among them looked forward to a profitable autumn aloft and it got an appreciative round from the crowd.”

― Douglas Adams, The Restaurant at the End of the Universe

32
17
submitted 5 months ago by N0t_5ure@lemmy.world to c/news@lemmy.world
[-] N0t_5ure@lemmy.world 161 points 5 months ago

Trans Am Meetup

23
submitted 6 months ago by N0t_5ure@lemmy.world to c/pics@lemmy.world

Maybe some kind of corn snake? He's in southern California, and the bike path was along the San Diego river.

[-] N0t_5ure@lemmy.world 111 points 6 months ago

Being mature for your age is a marker of childhood trauma.

[-] N0t_5ure@lemmy.world 121 points 6 months ago

As someone that grew up with detached parents with whom I never had the relationship I wanted, I've come to recognize that it will never happen. My mother is now dead, and like my father, she lacked the capacity to engage in healthy relationships. The monologue in the "Free Churro" episode (S5E6) of Bojack Horseman really hits home for me, this point in particular:

I have this friend. And right around when I first met her, her dad died, and I actually went with her to the funeral. And months later, she told me that she didn’t understand why she was still upset, because she never even liked her father. It made sense to me, because I went through the same thing when my dad died. And I’m going through the same thing now. You know what it’s like? It’s like that show Becker, you know, with Ted Danson? I watched the entire run of that show, hoping that it would get better, and it never did. It had all the right pieces, but it just—it couldn’t put them together. And when it got canceled, I was really bummed out, not because I liked the show, but because I knew it could be so much better, and now it never would be. And that’s what losing a parent is like. It’s like Becker.

For anyone else in the same position, recognize that it is exceptionally difficult for people to change, and a necessary prerequisite is that they see change as necessary and want to change. Most are afraid of change and will never do it, to their detriment.

38
submitted 8 months ago by N0t_5ure@lemmy.world to c/asklemmy@lemmy.ml

I've been working on myself after coming out of a toxic long-term relationship that destroyed my social network, and am quite rusty at engaging with people I don't know. I'm also an introvert by nature, but am capable of overruling that nature and engaging with people when I consciously try. At this point I feel like I just need to boost my experience and restore a level of comfort in engaging with people I don't know. When I go out (by myself), I tend to go see live music, which is fun but generally not conducive to conversation. Ultimately I'd like to restore my rusty social skills for the purposes of interacting with members of the opposite sex, but at this point I just need to work on engaging with people in general. WHat say you, people of Lemmy?

91
submitted 8 months ago by N0t_5ure@lemmy.world to c/news@lemmy.world

For nearly a decade Elon Musk has claimed Teslas can truly drive themselves. They can’t. Now California regulators, a Miami jury and a new class action suit are calling him on it.

[-] N0t_5ure@lemmy.world 90 points 8 months ago

He's got to be getting under Trump's skin. The worst thing you can do is ridicule a narcissist, as they hate being laughed at.

[-] N0t_5ure@lemmy.world 127 points 8 months ago

I'm not a big fan of Newsom, but this is a good parody of Trump's messaging. I chuckled.

47
66

Given the transition, you'd think Trump would be more accepting of trans rights!

41
submitted 9 months ago by N0t_5ure@lemmy.world to c/asklemmy@lemmy.ml

I'd say 2005-2015. Mature enough to be useful, but didn't really go to shit yet.

198
submitted 10 months ago by N0t_5ure@lemmy.world to c/memes@lemmy.world
[-] N0t_5ure@lemmy.world 104 points 10 months ago

Lol. I wonder how quickly the Trump administration will get this before the Supreme Court.

[-] N0t_5ure@lemmy.world 108 points 1 year ago

Jeremy Clarkson recently declared victory over Musk:

"I said it was unreliable, which it was; that it was ridiculously expensive, which it was; and that because it weighed more than most moons, it didn’t handle very well. Which it didn’t.

"Musk was very angry about this and sued us for defamation, claiming I had a problem with electrical cars and had written the piece before even setting foot in the car.

"He lost the case, and the appeal, and he’s never really got over it. He still claims I was biased and that we pretended his car had broken down when it hadn’t. Even though it had.

"I should really have sued him back, but I feared he’d call me a paedo, so instead I just waited on the river bank for his body to float past. And now it has."

view more: next ›

N0t_5ure

joined 1 year ago