Don't know, not using ublock origin. I use enhancer for YouTube on Firefox, and still not seeing any pop up.
Tho I have it set to allow ads for subscribed channels. Tho the setting seems bugged as a feature where most video ads get blocked, but some of them still run sometimes at the start of the video. The square adds on the side aren't blocked either, but they are not a hindrance.
I don't use chromium, did not test currently.
But I just saw a video about a chromium browser : Thorium.
It's chromium but with many hardware acceleration, speed, and compatibility enhancements coming from multiple sources and from the guy developing it on github, making it very fast and nicer to use than default chromium.
It has Google sync, so it's not ungoogled, but it has way less bload and more privacy than chrome.
https://youtu.be/naDYUVFs1-8?si=Rd6Un0OKANEQHktH
The link to the browser website : https://thorium.rocks/