I have had some problems with PipeWire as JACK replacement, mostly it was some tearing artifacts that were very annoying. Recently though I learned how to use PipeWire (which is great for general desktop audio usage + works with Bluetooth really good) with JACK for pro-audio applications. By using the JACK DBus detect module it is possible to turn PipeWire into JACK client when ever the latter one is started.
So this way it is not required to use PulseAudio at all with JACK. There's also possibility to use PipeWire as JACK server because it also provides such API.
Yeah, but you have compared top-of-the-line Ryzen model vs. Intel's high-medium tier. That's not gonna really help.