I had forgotten about Pipewire, an incredible project. Fedora is a great OS, I had always thought RH had more claws into Fedora than they seemingly do. Nice to know it's community managed.
Silverblue is something I need to sit down and play with properly. Arch makes sense for gaming and development, with the packages being so hot off the production line. Is Silverblue your more daily driver 'needs to be stable' OS?
Lots of developers seem to love NixOS, I think I'm with you in not having been able to set it up exactly how I wanted. Silverblue is definitely on the 'play with' list.
I use Alpine for containers (LXC usually, sometimes Docker). Super tiny, very very minimal.
apk add <package>
and you're golden. PostmarketOS even gets basically Alpine working on things like Pinephones, which is fun to play with.