In 5+ years, when I may have HDR on my desktop, Gnome will be more than ready. (:
I remember a time, when you have to wait for hardware support. But maybe monitors just aren't the thing you buy every 2-5 years. Mine is more than 10 years old and very sufficient.
For a long time I considered Gentoo the best, because I know my things around there. A month ago I said goodbye to my last Gentoo installation in favour for Debian trixie (the next stable release). Gentoo was too time consuming despite the binary repo.
If it would be my job to maintain a Gentoo system I would gladly accept, but there should be a need for it by the users. Otherwise I would just recommend Debian stable or Fedora.
My favourite is Debian over Fedora, because I often don't need the latest versions of a software. And there is flatpak.