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Phantom clicks on desktop
(sopuli.xyz)
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The mouse randomly clicking is noticeable already at the user log in screen, so I'm going to risk creating a new account will retain the strange behaviour.
You did manage to make me think there are two DEs on the machine and, maybe, by some weird event, there is an overlapping conflicting mouse controller.
Booting from a thumb drive is going to be very useful and I thank you for that suggestion. If the latest ISO running live replicates this behaviour, then there is the possibility there is a bug I can report.