If it still works like it did in the original, putting some sliders up will move others back, but it isn't equal, so you can ping pong between the sliders that are meant to be mutually exclusive and get both to levels that they shouldn't be able to get to simultaneously.

Edit: Also, the sims with slider unlockers gets even worse than Oblivion, as the game will use the unlocked/modded sliders when it generates random townies. I love my town of goblins with half inside out faces.