In Deadly Premonition 2 you get your standard incest plot with a side of transphobia since the brother in question here is actually a trans woman. The game came out in 2019 but feels like it was written in 2005 with how the character's gender is handled
The game is just all over the place. Swery wrote an incestuous perverted trans murderer and constantly misgenders her but also has several scenes where Francis York Morgan chastises small town hicks for their transphobia 
Obviously Swery didn't consult anyone while writing the game and it's interesting no one in the localisation/translation team flagged these issues in the script either. Swery got predictably pilloried on Twitter when the game came out on Switch and they scrambled to patch the game to make the dialogue less offensive. Yes, the PC version you see here is the patched version of the game 
Aside from all the transphobia, there's plenty of other iffy shit going on with the game's writing. The main villain is building up to be a black guy and his monstrous, morbidly obese blonde wife which feels a bit weird with how many of the game's black characters are written, like the black lady who starts every sentence with OH LAWD. There's also a running theme of older male characters being in love with much younger female characters, the most extreme example being a 16-year-old girl dating an adult man that looks to be in his thirties which is NEVER REMARKED UPON and treated as completely normal. York also has a 10-year-old girl sidekick in this game and some of the shit he says to her just comes off as really fucking weird sometimes
Francis Discord Mod Morgan
I'm nearing the end of the game and it's just shocking how bad Deadly Premonition 2 is compared to the original. The graphics and gameplay being absolute dogshit could be explained by the game having basically no budget but how the fuck is the writing so awful when that was the glue holding Swery's previous games together
Libertarian brainworms have also affected Japan it seems
The heavy use and emphasis of casual anti-black racist caricatures and stereotypes in Asian media deserves analysis. And I say this as someone in SEA
Black characters in anime be like
YO! SOUL! FUNKY
Mr. Popo from Dragon Ball
People in other countries are usually basing their perceptions of black people on American propaganda and media, and it is extremely right wing and often racist. And the more pro-American someone is, the higher the probability that he would be very racist.
The part you quoted was also in Baki hanma prison episode whatever his name was fights Che guevara. His wife was in a state where she couldn't get out of bed. The series was mostly a bit and I checked it from the middle randomly and landed on the Che guevara bit. (Che defeated Amerikkka with just a few trained men all with their bare hands without firing a shot and also he was a pirate ) I dropped it at part where the guy he was fighting bought his wife while she was on the bed on the prison grounds to fight Che and the prisoners were trying to laugh but couldn't because they were scared of him.