I'm not a huge fan of the isekai genre, but that doesn't mean I hate it either; its ubiquity is what makes me wonder why people don't just make straight up fantasy anime.
Frieren for example would be terrible if Frieren was actually some random person from earth who got sent into her setting (or, as Frieren's whole thing is outliving her comrades, her purple haired protege was the isekai'd protagonist); I understand how the isekai nature of an anime can also affect the anime, for example a character who has modern world knowledge he applies in the setting, or modern world tech, but if he just becomes a part of it, and NOTHING from his real life has any impact on the setting....then what's the point?
Overlord for example (which I didn't enjoy to be honest; I googled if he ever faces a challenge and nope, entire series and he has zero things that can challenge him) would not have been affected if he was just some lich who woke up a thousand/hundred years later.
Konosuba benefits from the isekai genre in that the isekai elements keep being relevant throughout (Spoilers:
spoiler
for example that guy who chose to reincarnate into the world with a powerful sword that Kazuma stole, or Kazuma dying and Aqua's replacement reviving him repeatedly, or that the demon lords at some point realized all their most annoying hero enemies keep starting in this one town and so decide to attack it, or that ancient scientist who turns out to be have been an isekai'd hero who creates stuff inspired by stuff he was a fan of
Most isekai animes today just seem to be wish fulfillment harem animes, which are a problem on their own as well, but they're paired with being isekais too (if you're wondering why I didn't make a thread on wish fulfillment harem animes, it's cause by and large I avoid them like the plague).
There are some interesting POST isekai stories that I found fascinating, stories where the characters came back from the isekai world and had their powers with them; in one case some of the heroes become devastatingly powerful villains who destroy entire cities, in another case it's a comedy about some guy who comes back and....could have been funnier without the ecchi/SA nonsense happening throughout.
Animes like SAO (which I didn't find interesting beyond the first story) make the other world an entirely false world and never let you forget the characters are real people who can actually die in the real world (sort of an anti-isekai genre).
In general, if they're not going to benefit from being isekai....then just make them normal fantasy. So many good fantasy animes out there that would have been hurt by making the protagonist just an isekai'd character.
Sci-fi is the People’s Fiction.
Imagine a future where the working class won and humanity is embracing life in the galactic federation. Hard to be a self-important chud when you’re regularly dealing with aliens from different planets all happy to share their stories with you.
Actually on a further note, I've wanted to do multiple skits on a Stellaris diplomat who eventually meets the WH30k Imperium and despises them after they wipe out several friendly alien planets
When I was growing up (back when I still had the energy and excitement to do anything) there were so many stories I wanted to write, and your post reminds me of the stories I wanted to tell.
I recall a (very) short story in the game of Myst where these dimension travelers find a world of green monkey people who are kind to them and have a friendly nature as well, who I think even tell them stories; this short story was so fascinating it got me to buy the Myst novel.....the Myst novel is dull; it feels like 70% of the writing is descriptions of the world, and the plot moves very slowly and PERHAPS it's supposed to get interesting, but I could never finish it.
I'm too lazy and demotivated to write, but I've had a bug about making youtube shorts inspired by Stellaris; alas I see genuinely well done skits (some of my favorite content creators like Cilvanis and Calebcity are genuinely HUGELY talented; if there was any doubt about how hard it is, or how much talent it takes to do what they do, Cilvanis offers a very useful video where he shows some of his friends/former friends who ripped off his skits, and they're done POORLY in comparison) and I just feel I'd do a terrible job; also I absolutely won't show my face for anything I do, I am NOT having my face out there, even if others will.