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this post was submitted on 23 Apr 2026
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ADHD
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It is my understanding that part of the effect, especially the medically desired effect, does not build (much) of a tolerance. The part that feels like a recreational drug does, but it'll still regulate noradrenaline in the prefrontal cortex all the same with the starting dose.
These are hard to exactly tell apart, though; it's a blurry line.
Yes I think so at least for methylphenidate and vyvanse. I also think its important to eat a lot of protein in the morning for vyvanse to gain its potential or it can just not work as it should and people might be tempted to increase dosage with negative consequences.