The problem I have with artificial environment is that humans (and all life on Earth) evolved in natural environment trough many many years. Can we be so certain that artificial environment (food, cosmetics, ...) are not triggering undesired response, body trying to adopt to synthetic materials, what would be the outcome? I'm thinking about cancer, auto immune disease and similar.

We only observe consequences and for some it might take a lot of time to show, but then it might be too late to fix, or, fix in a hurry could make it even worse.

I always ask myself, for example, how long it took giraffe to develop long neck, why, and so on. It didn't happened in 100 years, 3 - 4 generations.

How many food is now labeled "unhealthy" that was "healthy" few years back, or even medicine, this recent anti congestion in Sudafed (I think). There are examples everywhere.

We should be more humble and less arrogant when trying to understand complexity of nature and its processes.