66
you are viewing a single comment's thread
view the rest of the comments
view the rest of the comments
this post was submitted on 25 Sep 2023
66 points (89.3% liked)
Asklemmy
43989 readers
787 users here now
A loosely moderated place to ask open-ended questions
If your post meets the following criteria, it's welcome here!
- Open-ended question
- Not offensive: at this point, we do not have the bandwidth to moderate overtly political discussions. Assume best intent and be excellent to each other.
- Not regarding using or support for Lemmy: context, see the list of support communities and tools for finding communities below
- Not ad nauseam inducing: please make sure it is a question that would be new to most members
- An actual topic of discussion
Looking for support?
Looking for a community?
- Lemmyverse: community search
- sub.rehab: maps old subreddits to fediverse options, marks official as such
- !lemmy411@lemmy.ca: a community for finding communities
~Icon~ ~by~ ~@Double_A@discuss.tchncs.de~
founded 5 years ago
MODERATORS
Everyone's biochemistry is different, that's why we had the opioid epidemic and not an opioid pandemic...
It might work on others, but not you. And for a decent amount of people it works for, a significant amount are having the placebo effect.
So just go into it with an open mind thinking it may relax you, and it might. Even though I've just told you it could be placebo, that doesn't hurt it's chances. (Crazy side note: the opposite of a placebo is a nocebo, something that gives a negative effect. Being aware of that does prevent it).
If you do it for a while, simply the act of putting a kettle on would have you relaxed before you've taken a drink. It doesn't matter why it works, just that it does.
Maybe. But I think there are also just a lot of people that are not dealing with enough trauma and mental pain (pain-killers/type not specific) that their inner voice stops them from seeking it out.
My dad had a friend with brain cancer. He was in hospice many years ago and knew that I had struggled with addiction. He said he had received hydrocodone and oxycodone after surgeries before (he'd had many) but they always made him nauseous and feel like shit. Then at the end when he was in hospice they gave him a fentanyl patch. He said "MyName, WOW, I FINALLY UNDERSTAND how people can get addicted to this stuff now. This is remarkable!"
Off-topic story: shortly after he passed I was looking for ways to painlessly "catch the bus" on the internet (I'm fine now, this was many moons ago) and bawling my eyes out as I thought about my family and what I'd be putting them through. Suddenly, the piano next to me blasted as if someone had pounded 10 of the keys at once as hard as they possibly could. No pets, no other people home.
I've been through a lot since then and am happy to say I am doing fine now, but that's one of those many WTF moments that turned me from a staunch materialistic atheist into a more spiritually understanding person.
That and the DMT. Only slightly riffing, DMT came way before that.
Well, yeah...
Your first example needs metabolized into an active ingredient. The second is an active ingredient.
There's a bunch of different liver enzymes at play, and an absolute shit ton of normal variation between people.
Too much of those enzymes, and you burn through a 12 hr oxy in 6 hours, which makes people likely to abuse their own medication and can lead to life long addicts.
Too little and you get zero effect from "normal" opioids, but fentanyl, morphine, and other direct action opioids stick around for a lot longer and you have no tolerance.
That's what I'm saying:
Yes I was just sharing a side-thought while agreeing and sharing a story.
There's a convention or interpolation wirh regard to opioids/opiates such that: