Can DXM (dextromethorphan) be used to prevent or reduce tolerance to other ligands? (lemmy.world)

submitted 1 year ago by cheese_greater@lemmy.world to c/asklemmy@lemmy.ml

18 comments fedilink hide all child comments

There's drugnerd whispers on the internet that DXM (microdosed) can block or attenuate the development of tolerance to various ligands, particularly amphetamine.

Any DrugNerdz here who can explain the valudity of this conjecture or expand on it in any helpful way

you are viewing a single comment's thread
view the rest of the comments

[-] givesomefucks@lemmy.world 19 points 1 year ago

To this day my body won’t let me swallow anything with that sugar coating on it.

Man, I feel like everyone that did a lot of robotripping all hit that point (pretty quickly) where they have to stop.

Not because they want to get clean, not because they have a bad trip, but their body just draws a line in the sand that it's not accepting anymore dxm...

Never heard of it happening to a crackhead or alcoholic. But at some point everyone's body just rebels against cough medicine.

[-] EchoCT@lemmy.ml 3 points 1 year ago* (last edited 1 year ago)

Yep. Can confirm, I can't even look at them anymore without feeling that bile rise.

That said. I miss MXE. Since the UK banned it I haven't found it anywhere.

[-] MuhammadJesusGaySex@lemmy.world 1 points 1 year ago

It’s crazy how that happens. At first those sweet pills weren’t bad at all. But eventually it’s like my body associated that taste with what’s about to come and tried to preemptively sabotage me. That stuff is weird.

[-] intensely_human@lemm.ee 0 points 1 year ago

That’s why I stopped mixing the mushrooms with nice tasting stuff to mask it.

I melted a pan full of chocolate once and suspended little diced shrooms in it. Hey nice right? Nope I couldn’t eat chocolate for a year afterward.

this post was submitted on 21 Oct 2023

25 points (93.1% liked)

Asklemmy

43852 readers

676 users here now

A loosely moderated place to ask open-ended questions

Search asklemmy 🔍

If your post meets the following criteria, it's welcome here!

Open-ended question
Not offensive: at this point, we do not have the bandwidth to moderate overtly political discussions. Assume best intent and be excellent to each other.
Not regarding using or support for Lemmy: context, see the list of support communities and tools for finding communities below
Not ad nauseam inducing: please make sure it is a question that would be new to most members
An actual topic of discussion

Looking for support?

Looking for a community?

Lemmyverse: community search
sub.rehab: maps old subreddits to fediverse options, marks official as such
!lemmy411@lemmy.ca: a community for finding communities

~Icon~ ~by~ ~@Double_A@discuss.tchncs.de~

founded 5 years ago

MODERATORS