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They're slow and don't even have weapons.
(startrek.website)
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How bout a zombie like virus that keeps the tissue alive but causes the conscious to fail avoiding say water but aggressively biting others, usually without killing them so the infection can run its course.
I was told that rabies just isn't very good at infecting humans which is why you don't see nightmare situations with it. One person dies, not an entire town.
Unless it kept enough mechanisms intact to retain a good amount of self preservation, it would fail. If it avoided water actively, it would die from thirst.
Aggression is not a controlled impulse. It's blind and does not measure outcome. How much would be enough to ensure transmission? A bite to the arm? Perhaps to the leg? Awfully specific.