In-lore I don't think so, no, but in-game is uneven. IIRC the inability to communicate at FTL speeds never actually becomes relevant. Some quests finish as soon as you complete them (a lot of faction bounty board stuff I think, the constellation surveys for sure), and other times NPCs react as though they were able to receive intel about your work in another system before you get back even though you fast travel directly there. But most of the time it's "go through 30+ seconds load time on an SSD and watch multiple unskippable cutscenes to complete".