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The Standing Committee on Vaccination (STIKO) has entered its COVID-19 vaccination recommendations in the immunisation schedule for recommended standard vaccinations. Healthy people aged between 18 and 59 years (including pregnant people) are recommended a basic immunisation as well as a booster to build up a basic immunity. It is important that the immune system is exposed to pathogen components (through vaccination) or the pathogen itself (through infection) three times. At least two such exposures should occur through vaccination.

Groups of people who are at increased risk are recommended an additional booster vaccination once a year. The vaccination should be administered with a variant-adapted vaccine and generally at least 12 months after the previous vaccination or infection. Preferably vaccinations should be administered in autumn, so that in case of growing infection rates, vulnerable people still have the best-possible protection in autumn and winter.