Yes, there is always something that won't work. This often happens with Windows (not too often, but it happens), but most often with Macs. Linux is quite buggy in the userspace area, I usually find bugs or crashes within an hour of using any linux distro. The one with the FEWER bugs is definitely Debian. But it does that by not using hacks or beta drivers or software. This creates a rock solid architecture, but some hardware won't work (in my case, it was the sound chip for an intel J-series cpu that required a third party patch to work and recompile the kernel -- while Ubuntu ships with that patch by default, but ubuntu has way more other bugs all around).

So at the end, you will have to ask yourself if you want Linux because it's the right thing to do and use, or you just don't want to be bothered with ideology, and just use Windows and be done with it. I've asked myself that question and the answer is two fold: as a daily browser laptop, that doesn't depend on third party hardware, I just use my Macbook Air. It's a great laptop to have around in front of the TV, or traveling. For third party hardware dependency, and video editing, I use Windows with an nvidia card. For everything else, I use Linux. I have 8-9 computers, most run Linux. I create databases with it, I do some photo editing, financials etc.