You provided the hypothetical. If my hometown was a hotbed of insurgents or something and it would be a strategic blow that would bring a swift conclusion to the Civil War, I wouldn't think too hard on it. I'd certainly need to know why though (I'm not interested in being involved in war crimes).

But I'll never be in that position. I'm past draft age, so I'd likely be defending my house, not bombing targets. But if somehow I was involved, I'd press the button if I was convinced it would target belligerents and end a lot of the fighting, hometown or not.