Yes, in various ways.

One part is immediate. When I'm nervous or keep worrying about something, going for a run almost certainly resets my flow of thoughts. It also burns off most of the tension, at least I have a much easier time relaxing after a workout.

The other part is more long-term. Despite many, many years of running, it merely helped keep my weight in check rather than give me a dream body, but it seems to have changed my thinking a bit -- not like some motivation guru's story where someone forces themselves through hardship to develop a warrior mentality stuff, though. It's more like becoming aware, long after the change happened, that, woah, I may have skills now.

As in, there is no mental talk-back or willpower needed for me to run up a steep mountain trail in my area, the gist is more: no question that I can do it, it will be cool to experience it again. For a long time, I wasn't even aware that it's not always been that way. It also doesn't seem to rub off on other areas of life like one would hope, but just having proof in myself that I may have built up to something is a small confidence booster.