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It’s not that synthetic opiods should be legalised. Heroin should be legalised on prescription, in the same manner as methadone. And an equivalent stimulant for stimulant addicts.
In combination with available rehab and mental health treatment this leads to significantly less drug users and a change in the cultural attitude to drugs.
If the aim is simply to eradicate drug use to the maximum extent, that can also be achieved via state violence. That would carry greater dangers, costs and ethical concerns, so that the cure would turn out to be worse than the disease.
Mao’s success was achieved within the context of a revolutionary society. Drug reform is possible without even needing to take on the status quo, other than relatively minor vested interests like the police. And in some theoretical revolutionary context, it’s obviously not desirable to inflict unnecessary violence, indeed that’s one of the reasons that China, the USSR and other communist states ended up becoming revisionist, because of an excess of needless revolutionary violence.