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Quake-like game made with JavaScript takes up just 13KB of storage
(www.tomshardware.com)
This is a most excellent place for technology news and articles.
in the case of kkreiger, absolutely... Uninstall the wrong font in windows and you actually break kkreiger. So it's not even fully self-contained and relies on static windows assets to function.
It also needs DirectX, which is another 70-100MB depending on the version.