Hopefully I'm preaching to the choir and the main response from everybody is that this is obvious and didn't need to be said.
I read a few comments from some gross cishets about how angry they are about the female Custode. They prop up the Imperium of Man as though they are some paragon of morality and not the picture of everything wrong with imperialism. Naturally this perfectly moral force would have only men in its ranks, clearly! They don't seem to realize that if women are left out we have a sexist/mysogynist system which is not worth praising, and if they include women then it's the imperialist machine trying to keep up appearances. Frankly, I've always figured the Imperium didn't care about gender or race because everyone is suitable to die in combat and be ground into food for the starving populace.
tl;dr Men are upset that women exist and missed the whole satire
My headcannon has always been that the Imperium is too concerned with high tech, enlightened forms of bigotry we could barely comprehend to worry about paltry shit like gender and race. They don't give a shit what your skin color is, unless it's more than 3 standards of deviation from normal, in which case they shoot you for being a mutant.