Not exactly OTC but there's a lot of evidence for psychedelic therapy. I get ketamine injections at a clinic and take mushrooms regularly to try and spread out the super expensive k injections. I'm going for my next shot tomorrow, seeing as I've become an emotional trainwreck while the estradiol starts to take hold. If you can get your hands on it, 4-ACO-DMT is the closest you can get to psilocybin. I would 10/10 recommend. Nothing has ever made me feel better.