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Wolverine is a mutant and was born that way, but the experiments added the whole indestructable skeleton on top of that. The only reason he survived the experiments in the first place was because he's got crazy fast healing as a mutant power.
However, Deadpool might fit the bill, at least in some versions. He was given Wolverine's healing factor in the same Weapon X project. It's actually super powerful and would kill him if it wasn't in a constant deadlock with his cancer which is also constantly killing him. There was a comic where Norman Osborn attempted to assassinate him by shhoting him with a cure for cancer...
Cheers!
That's an interesting take, because it is a plausible origin story arising from an "implausible" one! What I mean is that, according to the (admittedly not well defined) "bounds" of my original post, mutants have a less believable origin story since they're just born with powers, but Deadpool becomes a superhero since he already lives in a universe where mutants and healing factors exist and so it makes sense they make experiments on it!
I didn't know Norman Osborn tried to kill Deadpool with a cure for cancer. That's a neat plot device!