Science

Doctors in the US have become the first to treat a baby with a customised gene-editing therapy after diagnosing the child with a severe genetic disorder that kills about half of those affected in early infancy.

KJ was born with severe CPS1 deficiency, a condition that affects only one in 1.3 million people. Those affected lack a liver enzyme that converts ammonia, from the natural breakdown of proteins in the body, into urea so it can be excreted in urine. This causes a build-up of ammonia that can damage the liver and other organs, such as the brain.

Writing in the New England Journal of Medicine, the doctors described the painstaking process of identifying the specific mutations behind KJ’s disorder, designing a gene-editing therapy to correct them, and testing the treatment and fatty nanoparticles needed to carry it into the liver. The therapy uses a powerful procedure called base editing which can rewrite the DNA code one letter at a time.

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Antibiotics From Human Use Are Contaminating Rivers Worldwide, Study Shows (www.mcgill.ca)

submitted 4 days ago by shreddy_scientist@lemmy.ml to c/science@lemmy.ml

0 comments fedilink

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Universe expected to decay in 10⁷⁸ years, much sooner than previously thought (phys.org)

submitted 5 days ago by yogthos@lemmy.ml to c/science@lemmy.ml

10 comments fedilink

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Engage in the 5th International Polar Year: opportunities and updates for ISC Members (poliversity.it)

submitted 3 days ago by giotras@poliversity.it to c/science@lemmy.ml

1 comments fedilink

Engage in the 5th International Polar Year: opportunities and updates for ISC Members

@science

https://council.science/news/ipy-5-updates-opportunties/?utm%5C_source=rss&utm%5C_medium=rss&utm%5C_campaign=ipy-5-updates-opportunties

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Sleep Helps Your Brain Prepare For The Future, And Now We Know How (www.sciencealert.com)

submitted 6 days ago by yogthos@lemmy.ml to c/science@lemmy.ml

1 comments fedilink

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ALICE detects the conversion of lead into gold at the LHC (www.home.cern)

submitted 1 week ago by yogthos@lemmy.ml to c/science@lemmy.ml

3 comments fedilink

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Doomed Soviet spacecraft Kosmos 482 could hit Earth tonight. Here's when. (www.livescience.com)

submitted 1 week ago by Zerush@lemmy.ml to c/science@lemmy.ml

5 comments fedilink

They have bets on where it hits (I see some wishes)

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“They’re drilling to the core of the Earth”: China starts a 32,800-foot drill into unexplored layers. (farmingdale-observer.com)

submitted 1 week ago by yogthos@lemmy.ml to c/science@lemmy.ml

2 comments fedilink

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Scientists Confirm the Incredible Existence of ‘Second Sound’ (www.popularmechanics.com)

submitted 1 week ago by yogthos@lemmy.ml to c/science@lemmy.ml

2 comments fedilink

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New Perspectives on the Enigma of Expanding Antarctic Sea Ice (eos.org)

submitted 1 week ago by yogthos@lemmy.ml to c/science@lemmy.ml

0 comments fedilink

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Chinese scientists unlock gene secret at root of drought-tolerant rice (www.scmp.com)

submitted 1 week ago by yogthos@lemmy.ml to c/science@lemmy.ml

0 comments fedilink

https://archive.ph/qvR6N

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New ISC survey explores Members’ science diplomacy priorities and capacities (poliversity.it)

submitted 1 week ago by giotras@poliversity.it to c/science@lemmy.ml

0 comments fedilink

New ISC survey explores Members’ science diplomacy priorities and capacities

@science

https://council.science/news/isc-survey-sciencediplomacy/?utm%5C_source=rss&utm%5C_medium=rss&utm%5C_campaign=isc-survey-sciencediplomacy

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Rethinking science in a complex world- insights from Craig Calhoun (poliversity.it)

submitted 1 week ago by giotras@poliversity.it to c/science@lemmy.ml

0 comments fedilink

Rethinking science in a complex world- insights from Craig Calhoun

@science

https://council.science/blog/rethinking-science-in-a-complex-world-insights-from-craig-calhoun/?utm%5C_source=rss&utm%5C_medium=rss&utm%5C_campaign=rethinking-science-in-a-complex-world-insights-from-craig-calhoun

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Shaping the future: Insights from futures thinking and strategic foresight in the Global South (poliversity.it)

submitted 1 week ago by giotras@poliversity.it to c/science@lemmy.ml

0 comments fedilink

Shaping the future: Insights from futures thinking and strategic foresight in the Global South

@science

https://council.science/news/shaping-future-insights-futures-thinking-strategic-foresight-global-south/?utm%5C_source=rss&utm%5C_medium=rss&utm%5C_campaign=shaping-future-insights-futures-thinking-strategic-foresight-global-south

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Shaping the future: Insights from futures thinking and strategic foresight in the Global South (poliversity.it)

submitted 1 week ago by giotras@poliversity.it to c/science@lemmy.ml

0 comments fedilink

Shaping the future: Insights from futures thinking and strategic foresight in the Global South

@science

https://council.science/news/shaping-the-future-insights-from-futures-thinking-and-strategic-foresight-in-the-global-south/?utm%5C_source=rss&utm%5C_medium=rss&utm%5C_campaign=shaping-the-future-insights-from-futures-thinking-and-strategic-foresight-in-the-global-south

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Call for science writers (poliversity.it)

submitted 1 week ago by giotras@poliversity.it to c/science@lemmy.ml

0 comments fedilink

Call for science writers

@science

https://council.science/news/call-for-science-writers/?utm%5C_source=rss&utm%5C_medium=rss&utm%5C_campaign=call-for-science-writers

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Call for editing services | deadline 31 May (poliversity.it)

submitted 1 week ago by giotras@poliversity.it to c/science@lemmy.ml

0 comments fedilink

Call for editing services | deadline 31 May

@science

https://council.science/news/call-for-editing-services-deadline-31-may/?utm%5C_source=rss&utm%5C_medium=rss&utm%5C_campaign=call-for-editing-services-deadline-31-may

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Invasive Crab With Furry, Mitten-Like Claws Detected for the First Time in the Pacific Northwest (www.smithsonianmag.com)

submitted 1 week ago by yogthos@lemmy.ml to c/science@lemmy.ml

0 comments fedilink

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Trees which benefit from being struck by lightnings (nph.onlinelibrary.wiley.com)

submitted 1 week ago by Zerush@lemmy.ml to c/science@lemmy.ml

0 comments fedilink

Some tropical trees (Dipteryx oleifera) benefit of being struck by lightning, which is not harmful for these, but frees them from parasites and competitors.

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Heart Disease Deaths Worldwide Linked to Chemical Widely Used in Plastics (nyulangone.org)

submitted 2 weeks ago by shreddy_scientist@lemmy.ml to c/science@lemmy.ml

2 comments fedilink

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Exercise can counter side-effects of cancer treatment, biggest review of its kind shows (www.theguardian.com)

submitted 2 weeks ago by geneva_convenience@lemmy.ml to c/science@lemmy.ml

0 comments fedilink

Exercise can counter the detrimental effects of cancer treatment, according to the most comprehensive review of its kind.

Several studies have evaluated how physical activity affects the health outcomes of patients with the disease, but significant gaps in the evidence have remained until now.

The review of pooled data analyses of randomised controlled trial results published between 2012 and 2024 suggests that exercise can significantly reduce side-effects associated with treatment for cancer, such as heart and nerve damage and brain fog. Before this study, no such comprehensive evaluation had been published.

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New panel of experts to tackle gender gap in science leadership (poliversity.it)

submitted 2 weeks ago by giotras@poliversity.it to c/science@lemmy.ml

0 comments fedilink

New panel of experts to tackle gender gap in science leadership

@science

https://council.science/news/expert-panel-advancing-gender-equality-in-scientific-organizations/?utm%5C_source=rss&utm%5C_medium=rss&utm%5C_campaign=expert-panel-advancing-gender-equality-in-scientific-organizations