The meaning of the title becomes obvious at the conclusion of the episode when we discover that Ortegas' ordeal is an observational experiment.
It is Stardate 2198.7. Ortegas mentions that the strange phenomena that the region of space is known for is “the kind of thing Division 12 usually looks into.” This is the first mention of such a division, which in context might imply a kind of X-Files type investigative branch of Starfleet.
Ortegas keeps a picture of her kid brother Beto (she mutters in Spanish, “hermanito”) on her mantle, along with models of planes. Thanks to the screenshot people at the cygnus-x1 website, I can spot an SR-71 Blackbird, a B-24 Liberator, a Supermarine Spitfire but there’s a couple I still can’t make out (an F-117 Nighthawk, possibly?). There’s also a model of the current Constitution-class Enterprise and a Walker-class starship.
The science lab Spock and Uhura are in is the same set as was used for La’An’s katra-space in the previous episode, which appeared to contain Cetacean Ops. “Let’s light this candle,” was said by astronaut Alan Shepard when he was about to become as the first American in space on May 5, 1961, in frustration when the engineers were still debating whether to launch Freedom 7.
Ortegas is flying the shuttle Archimedes, named for the Greek philosopher best associated with the phrase “eureka” which, according to legend, he shouted when discovering the principle of displacement. In 2381, the Obena-class starship USS Archimedes was commanded by CAPT Sonya Gomez (LD: “First First Contact”). We also see that Archimedes is outfitted with blast shields.
“Five by five” is an expression that means everything is fine, or optimal. It dates back to World War II, measuring the strength and clarify of a radio signal (on a scale of 1 to 5). Una asks if Pike is jealous, referring to his first assignment out of the Academy as a test pilot (DIS: “Light and Shadows”).
Ortegas says her stardate is unknown, probably because her location is unknown. This goes back to the TOS series bible, which stated: “Stardates are a mathematical formula which varies depending on location in the galaxy, velocity of travel, and other factors, can vary widely from episode to episode.” This was to provide a Watsonian explanation as to why stardates in consecutive episodes might be out of sequence, and so writers didn’t need to worry about being sequential with stardates in other episodes.
Wormholes are indeed notoriously unstable, although some can remain stable for a long time, like the Barzan wormhole (TNG: “The Price”). The only known completely stable wormhole is the Bajoran wormhole connecting the Denorios Belt in the Bajoran System with the Gamma Quadrant, but that wormhole is constructed by the Prophets.
The USS Constellation (NCC-1017) was a Constitution-class starship which was under the command of CDRE (at this point CAPT) Matthew Decker when it was destroyed by the Planet Killer five years from now in 2267 (TOS: “The Doomsday Machine”). This is the first mention of Epsilon Indi III, although Epsilon Indi II and IV have been mentioned prior (TNG: “Eye of the Beholder” and DIS: “Terra Firma, Part 1” respectively). Epsilon Indi is a trinary star system 12 ly from Earth.
There is a very TOS/Sol Kaplan-ish music cue when Ortegas spots the Gorn, but I’m uncertain if it’s taken from TOS: “Arena”.
Uhura calls her shuttle simulation Kamili Alpha One. As mentioned in SNW: “Lost in Translation”, Kamili was the name of her pet cat, the name meaning “perfect” in Swahili.
The most famous example of the “enemies working together for survival” trope in science fiction is the 1979 novella Enemy Mine by Barry B. Longyear which was adapted into a movie in 1985. In Star Trek, the trope appears several times but is closest to the novella in TNG: “The Enemy”, TNG: "Darmok", DS9: “The Ascent” and ENT: “Dawn”, in that the reluctant alliance takes place in when both are stranded in a hostile environment.
Enterprise uses a static warp field to try and prop the wormhole open. In TNG: “Remember Me”, Wesley creates a static warp field, or bubble, in an attempt to recreate the Traveler’s actions in TNG: “Where No One Has Gone Before” but it results in the creation of a pocket universe when Beverley Crusher is caught in it. In TNG: “All Good Things…”, a static warp shell acted as a subspace barrier between time and anti-time. The gas giant has 396 moons. In contrast, Saturn has 274 moons as of 2025.
The idea of sending up a flare was also used in TOS: “The Galileo Seven” when Spock jettisoned the shuttle’s remaining fuel and ignited it, creating a signal that Enterprise could see. I leave it to your head canon as to whether now we can say Spock got this idea from Ortegas.
The alien that appears before Ortegas is a Metron, dressed in Roman/Greek-esque fashion like the Metron who appeared to Kirk did in TOS: “Arena”. The Metron’s reference to resetting the memory of the Gorn for humans in future is a way to resolve the biggest discontinuity between SNW and “Arena”, namely why Starfleet doesn’t seem to have heard of the Gorn (or the Metrons) despite them being major antagonists in SNW.