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Digital picture frame from a monitor or TV?
(feddit.org)
Get one of these Eink frames from waveshare. I have an older version without wifi, so i have to run a python script to e-inkify images on my laptop, copy to the SD card, put it into the frame, but the linked one doesn't need that.
Since pi zero 2w is just a linux box, you can ssh into from remote and add/remove images from the folder that the screen shuffles through. Heck you could set up an cron job for the pi to hop onto your network and sync a folder on the nas.
And you can ignore the AI thing on this if you want, it's a neat side thing, not integrated to the display functionality code.
Edit. Oh I didn't see you wanted very large like 16 inch, I think big eink panels are outrageously expensive still