If you flip the mouse over you should see a circular piece of plastic. Rotate this and it should be able to pop out, at which point the ball will also fall out. Inside you will see a pair of rollers and a wheel, all of which may have gunk on them. Clean off the gunk and make sure they spin properly. Replace the ball, the circular plastic, and then rotate the plastic to lock the mechanism.

For a moment I thought you were posting from the past

~~I didn't know you could still get mice with wheels. I've only seen optical ones in the past decade or two. I don't miss the mechanical ones.~~ Oh wait, you mean the scroll wheel. In the old days there were mice with wheels on the bottom to sense the mouse positioning.

For your mouse, I'd just take it apart if it is possible to do, and clean everything.

Get a good no residue contact cleaner. Unplug the mouse, then spray in the sides of the wheel opening and then work the wheel like a clitoris in a porno. Repeat a couple times. Give it time to dry then test it.

I thought you meant mouse wheel as in hamster wheel and I was really confused at the end of your post title.

Have you tried compressed air? It may not do anything if it's stuck in there but may be worth a shot.

Had this with mine, you have to take it apart. It's not that hard.

Only thing I could think of is contact cleaner. I’d make sure it’s compatible with plastic like the brand I buy. Contact cleaner is used for electrical products/circuits and is non conductive. I use it to clean the charging port of my phone when dust gets in there and my vape for similar reasons. Depending on the design of your mouse I don’t see why you couldn’t try flushing it with contact cleaner.

unfortunately... I don't think you can. You might be able to get some 90% IPA (use a fresh bottle. IPA absorbs water from ambient humidity.) and q tips and get it 'okay-ish' for now, but the rotary encoder is generally pretty heavily enclosed (precisely because of this issue.) Flooding the thing with IPA or, submerging it.... is not a good idea. I wouldn't recommend trying it unless you were willing to buy another mouse when it makes things worse.

Ifixit does have a guide for replacing them, you maybe be able to take it apart enough to clean it out more thoroughly.

I'd try alcohol swabs. They're great for stuff like this. For really tight spaces, soak a toothpick in alcohol.

But your filling it with alcohol plan would work, as long as you let it completely dry before using it.

I would just take it apart, personally, because there's no telling what it looks like inside.

Do you have an air compressor? Yes -> Use that. No -> Do you have a drinking straw? Yes -> use that -> Do you have lung capacity? Yes -> drinking straw No -> Do you have a fine brush? You see where this gets you? Right. Give a man an air bottle, and he can clean his mouse one day, show him how to think practically and he will be able to clean anything any day of his life.

Cleaned many wheels with just a Lysol or Clorox wipe, but not the bleach or peroxide kind. Take that one guys great description of working it like a clit in a porno, but with a wet wipe of some sort. Just keep rubbing it back and forth as you rotate the wheel. It eventually removes gunk off the wheel and frees up gunk inside. Let it dry a bit before plugging it back in. If you have alcohol wipes or just high concentration alcohol, even better than the wipes, but maybe you have one or the other on hand.

Those damn scrollwheel on logitech Gxxx mice are know to glitch like this. If it's not fixed after you cleaned it, it's time for a new mouse. Mine drove me crazy until I replaced it with an MX Master.

I use a paint brush, air compressor, cotton swabs and a tooth pick to clean mine when I'm too lazy to take it apart. Also if you have an air mattress, then you may have an air compressor.

I've only ever used it on musical instruments electronics, not anything as tiny and complicated as computer peripherals but Deoxit might be worth trying. It's good stuff