Aseprite is purpose-built for pixel art. You can either buy it, or compile it yourself for free. I highly recommend checking it out.
Libresprite is a Fork that has a flatpak for a precompiled free version
+1 for aseprite, it's great
Take a look at Kitra, it has much easier UI
Just correcting the name, it's Krita.
There's also KDE's KolourPaint, which might be good enough for some very simple edits.
KolourPaint is like the direct equivalent of MSPaint
The top contenders I have experience with is: -Aesprite. It's paid. It's good. Built solely for pixel art.
Free stuff: -LibreSprite- this is the open version of aesprite before it went paid. I don't know it It's still maintained or updated, but it may suit your needs.
-pixelorama- web based made in the godot engine.
Pixelorama is FOSS, cross platform, focused on pixel art and built with the Godot engine, it could be worth checking into
If you don't mind retro looking for something reminiscent of older paint programs for Amiga, I suggest Grafx2.
The website says it's a "bitmap paint program inspired by the Amiga programs โDeluxe Paint and Brilliance. Specialized in 256-color drawing, it includes a very large number of tools and effects that make it particularly suitable for pixel art, game graphics, and generally any detailed graphics painted with a mouse."
I am not good at digital art, so I don't use it often, but it is pretty interesting to me at least. It might be in your package manager, might not, depending on the used repositories. Otherwise they link to their gitlab page for nightly builds.
They have a link to a 3rd party distribution appimage, but it seems like you'd need to get it through something like the Wayback Machine if you want the appimage. I personally don't recommend that because it seems like it's gonna be an older file based on the site hosting it redirecting to a February 2021 post saying the repository holding it is read-only.
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