Other Chromium browser vendors have claimed that they will continue to support MV2 based content blockers, later revealing that they were unwilling to support the code once Google removed it.
Xitter doesn't load for me but this is quoting Brave so I'm not so sure about that
(edit: Though I think Brave has a builtin adblocker so you may not even need it. However, just don't use Chromium anything at all)
Additionally, E2E chats don't sync between devices (and iirc you can't use them on desktop at all), and group chats can't be encrypted at all.