[-] ArcticDagger@feddit.dk 20 points 2 months ago

You will transfer the economic copyright to most journals upon publication of the typeset manuscript meaning that you're not allowed to publish that particular PDF anywhere. However, a lot of journals are okay with you publishing the pre-peer reviewed article or even sometimes the peer-reviewed, but NOT typeset article (sometimes called post-print article). Scientific publishing is weird :-)

[-] ArcticDagger@feddit.dk 40 points 2 months ago

Ahh that's wack. The article it's based on is open-access: https://www.nature.com/articles/s41586-024-07856-5

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[-] ArcticDagger@feddit.dk 12 points 3 months ago

But if they know they're getting ecstasy, the improvement might originate from placebo which means that they're not actually getting better from ecstasy. They're just getting better because they think they should be getting better

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But Marks points out that the FDA typically follows the advice of its independent advisory committees — and the one that evaluated MDMA in June overwhelmingly voted against approving the drug, citing problems with clinical trial design that the advisers felt made it difficult to determine the drug’s safety and efficacy. One concern was about the difficulty of conducting a true placebo-controlled study with a hallucinogen: around 90% of the participants in Lykos’s trials guessed correctly whether they had received the drug or a placebo, and the expectation that MDMA should have an effect might have coloured their perception of whether it treated their symptoms.

Another concern was about Lykos’s strategy of administering the drug alongside psychotherapy. Rick Doblin, founder of the Multidisciplinary Association for Psychedelic Studies (MAPS), the non-profit organization that created Lykos, has said that he thinks the drug’s effects are inseparable from guided therapy. MDMA is thought to help people with PTSD be more receptive and open to revisiting traumatic events with a therapist. But because the FDA doesn’t regulate psychotherapy, the agency and advisory panel struggled to evaluate this claim. “It was an attempt to fit a square peg into a round hole,” Marks says.

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From the article:

But for the general public, the implications of the study are simpler. “A microwave is not a pure, pristine place,” Porcar says. It’s also not a pathogenic reservoir to be feared, he says. But he does recommend cleaning your kitchen microwave often — just as often as you would scrub your kitchen surfaces to eliminate potential bacteria.

[-] ArcticDagger@feddit.dk 16 points 3 months ago

From the article:

Squeezed in alongside their main projects, the investigation took eight years and included dozens of participants. The results, published in 2016, were revelatory [1]. Two to three months after giving birth, multiple regions of the cerebral cortex were, on average, 2% smaller than before conception. And most of them remained smaller two years later. Although shrinkage might evoke the idea of a deficit, the team showed that the degree of cortical reduction predicted the strength of a mother’s attachment to her infant, and proposed that pregnancy prepares the brain for parenthood.

[1] https://www.nature.com/articles/nn.4458

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[-] ArcticDagger@feddit.dk 11 points 3 months ago

I think that hypothesis still holds as it has always assumed training data of sufficient quality. This study is more saying that the places where we've traditionally harvested training data from are beginning to be polluted by low-quality training data

[-] ArcticDagger@feddit.dk 15 points 3 months ago

From the article:

To demonstrate model collapse, the researchers took a pre-trained LLM and fine-tuned it by training it using a data set based on Wikipedia entries. They then asked the resulting model to generate its own Wikipedia-style articles. To train the next generation of the model, they started with the same pre-trained LLM, but fine-tuned it on the articles created by its predecessor. They judged the performance of each model by giving it an opening paragraph and asking it to predict the next few sentences, then comparing the output to that of the model trained on real data. The team expected to see errors crop up, says Shumaylov, but were surprised to see “things go wrong very quickly”, he says.

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[-] ArcticDagger@feddit.dk 20 points 3 months ago

What they see as "bad research" is looking at an older cohort without taking into consideration their earlier drinking habits - that is, were they previously alcoholics or did they generally have other problems with their health?

If you don't correct for these things, you might find that people who are not drinking seems less healthy than people who are. BUT, that's not because they're not drinking, it's just because of their preexisting conditions. Their peers who are drinking a little bit tend to not have these preexisting conditions (on average)

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From the article:

As predicted, studies with younger cohorts and separating former and occasional drinkers from abstainers estimated similar mortality risk for low-volume drinkers (RR = 0.98, 95% CI [0.87, 1.11]) as abstainers. Studies not meeting these quality criteria estimated significantly lower risk for low-volume drinkers (RR = 0.84, [0.79, 0.89]). In exploratory analyses, studies controlling for smoking and/or socioeconomic status had significantly reduced mortality risks for low-volume drinkers. However, mean RR estimates for low-volume drinkers in nonsmoking cohorts were above 1.0 (RR = 1.16, [0.91, 1.41]).

Studies with life-time selection biases may create misleading positive health associations. These biases pervade the field of alcohol epidemiology and can confuse communications about health risks. Future research should investigate whether smoking status mediates, moderates, or confounds alcohol-mortality risk relationships.

[-] ArcticDagger@feddit.dk 17 points 4 months ago

Here's an actual explanation of the 'sneaked reference':

However, we found through a chance encounter that some unscrupulous actors have added extra references, invisible in the text but present in the articles’ metadata, when they submitted the articles to scientific databases. The result? Citation counts for certain researchers or journals have skyrocketed, even though these references were not cited by the authors in their articles.

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[-] ArcticDagger@feddit.dk 23 points 7 months ago

Could it be this fella who's hitting you up: https://claude.ai/login

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[-] ArcticDagger@feddit.dk 12 points 1 year ago

I know that in Lithuania, they drink lightly salted water: https://www.kaina24.lt/s/vytautas-mineralinis-vanduo/

So while I don't doubt your taste buds, I think it's a cultural thing whether a bit of salt in water tastes bad 😄

[-] ArcticDagger@feddit.dk 12 points 1 year ago* (last edited 1 year ago)

When talking about measurements, "precision" and "accuracy" have slightly different meanings See here

[-] ArcticDagger@feddit.dk 36 points 1 year ago

Both - they get donations and are funded by NLnet's NGI0 Discovery Fund

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ArcticDagger

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