I don't think the distinction between "stupid / non-stupid" is the important one to make. The important distinction, imo, is between "honest" and "dishonest".

If someone wants to honestly learn the answer to something, how could this be a stupid question? Even if all other people in the world do, in fact, know the answer, it still wouldn't qualify as a stupid question if asked in good faith.

However, there are so many questions asked in bad faith and not coming from a desire to learn something. These are the real stupid questions.

So, to answer your question: if you're feeling stupid for asking something, just think about your intentions: do you ask because you honestly want to know the answer? Go ahead, and know that in this case there are no stupid questions - only stupid answers.

If you stopped after patch 1.10 (with the runewords like Enigma or Infinity) all tried and true builds from then will still work well: Hammerdin, BlizzSorc, Javazon, Summon Necro, Trapsin, WindDruid, Frenzy Barb .... all still work well. The only "old" build that got hampered a bit is WW - Barb, because of the changes to attack speed. D2R mostly opens new possibilities and didn't nerf anything (aside from arguably WW - Barb)

Biggest change, imo, is the addition of Terror Zones. How this works is that a number of zones in each act can become terrorized (one at a time, lasts for 1 hour, changes to a different zone after that). When a zone becomes terrorized, the monsters there will adjust to your lvl+2 (champions and bosses adjust +4 / +5), with all consequences of that, e.g. they grant the respective xp and their treasure class also changes accordingly (which means they can drop better loot). Terror Zones open up after killing Baal in that difficulty, so you'd need to beat the game before you can start farming terror zones. However, these zones (in hell difficulty) are really one of the prime farming spots now and also help to level once you're in the 90's as you're not bound to xp penalties due to outlevelling monsters.

Second biggest change is the introduction of Sunder Charms (only obtainable in hell terror zones) which allow to break immunities (each immunity has their own charm). This makes it really viable to go for single element builds now.

BEside that there are a bunch of new runewords and fixes to skills (ias calculation has been changed on some skilles and next hit delay has been fixed among other things), which opened up quite a few new builds.

Mass Effect " ... someone else might have gotten it wrong ..."