chair is also fucked up, as are dude's shorts. and whatever object it is behind chair (caulk gun??)

that cheetah-leopard does have very short rear legs and unequal length front legs

there was a time when anthropic models would refuse any question related to medicine. not because they care that hard, mind you. it's because that bloated startup is ran by cultists and they were worried that chatbot will come up with a bioweapon

GHB is one of many date rape drugs that people also consume recreationally, and yeah i’m not sure why they love it!

it shares some of bits of appeal with alcohol and benzos. some people also use it to ride out stimulant comedown, or at least to catch some sleep after stimulant use, and this goes for regular stimulants of amphetamine type but also for ketamine (and psychedelics. not sure how much crossover is out there, but it might be a different type of user). i heard that it also has some anabolic effect, but using it for pre-workout would be unwise

i don't know what kind of approach to workplace drug testing is/was out there, but ghb/gbl is a combination of being rather polar and having no chromophore which all else equal, means that its detection is harder/different compared to other drugs, and being metabolized quickly and also being formed naturally at low levels, which means that detection window is short. ghb lacks groups that typically react with reagent-type tests and instead custom-made strip tests are needed, or lab testing

there also might be general mindset that they're so rational, that it's impossible for them to use drugs in harmful ways (famous last words). some people just think of it as an another tool in their toolbox, and figure out that something is wrong only when they wake up strapped to a bed, with half of their face burned and iv line attached, in a psych ward two countries over, if ever

this advice is specifically about sulfuric acid. it's denser than water, so if added to it it will sink diluting itself along the way, while also heating water around and making it float to the surface. if done opposite way, water won't mix immediately because of large density difference so neutralizatio heat will be deposited on surface between these two boiling water and throwing acid around. this matters less with other acids because less heat is deposited, and in some cases acid is less dense than water. but if you stir the acid quickly, you can do it either way as long as you control temperature. this also is the case when you need to mix two different acids

tldr you can do whatever you want as long as you know what are you doing

e: i've checked and heat of dilution is greatest for sulfuric acid, liquid HF is similar per gram, gaseous HCl and HBr are half of that per mol, other common acids 5-10x less esp as aqueous solutions and not neat. also the same happens when diluting acids with other solvents, like alcohols or ethers, these might be even worse because they boil at lower temperature

and then some bozo says that biology is just complicated chemistry and chemistry is just complicated physics and we can simulate physics

curious thing is that i never hear biologists or chemists saying that, only some physicists and techbros. just trying to simulate your way out of small organic chemistry problems will make you even more hopelessly lost than you were before

at least he didn't say he "fell on it" and it was totally an accident

the problem is that there is natural (as in, unmodified) cheap generic insulin available, it's just that it sucks compared to everything else. you see, insulin is a peptide that is supposed to appear, do some signalling, then disappear and unmodified insulin copies this thing exactly. the problem is, most of the time when peptide is supposed to work as a pharmaceutical, you don't want to do that, you'd like insulin to last longer than usual, which means changes to it that make breakdown slower, or adding something that makes it stick to albumin, which has similar effect because it hides insulin somewhere enzymes can't reach it and also it makes it start acting slower. this means less frequent dosing and less changes in insulin activity over time. there are also other insulins that start acting faster than natural, and this is also due to a couple of modifications in its structure

for another example, ozempic was not the first drug in its class, it's also a modified peptide, and it can be injected s.c. once a week, compared to previous iteration (liraglutide) that requires daily injections. if natural peptide is injected i.m. instead, its halflife is half an hour, and in serum it's only two minutes (it gets released a bit slower than it is metabolized)

manufacturing costs are about the same for any variant, most of it is in purification. patents for a couple of these have expired anyway by now, but if manufacturing is limited then price can be set arbitrarily high (see daraprim)

yeah all while ~~being a high school dropout~~ he never went to high school

Maybe their idea is that publicly embarrassing oligarch boss of that company would be more effective in getting them to either use source code or buying a license

death of millions for profit - solid business practice, congratulations and see you again at next shareholder meeting