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[-] FrenziedFelidFanatic@pawb.social 85 points 4 days ago

Dopamine does a lot of things. It does not cross the blood-brain barrier.

So taking this would be all side effects and no benefits

[-] Kolanaki@pawb.social 25 points 4 days ago

So taking this would be all side effects and no benefits

So it's basically the same as Prozac? 😩

[-] ALoafOfBread@lemmy.ml 33 points 4 days ago

If you have depression anxiety and find that Prozac (an ssri) doesnt work well, you might consider something that directly works on dopamine - like Buproprion (brand name = wellbutrin, a NDRI, norepinephrine dopamine reuptake inhibitor).

[-] CompactFlax@discuss.tchncs.de 11 points 3 days ago

I was a bit of not interested and not educated enough to know what a NDRI was while I was on it but it does make sense for ADHD and Depression symptoms.

The withdrawal from Wellbutrin was bad. I got brain zaps if I was 1hr late taking it; tapering and cessation was miserable.

[-] ALoafOfBread@lemmy.ml 3 points 3 days ago* (last edited 3 days ago)

I have gone off a few times over the years and didn't experience many side effects/withdrawals, but that is definitely not always the case - I've heard that it reeeaaally does not work for some people. Ymmv

Similar to your comment about ADHD, I feel like it helps me with some of my autism symptoms ("low support needs"/aspergers)

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this post was submitted on 17 Jun 2025
475 points (99.4% liked)

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