625
How about the digestive system?
(feddit.org)
A place for majestic STEMLORD peacocking, as well as memes about the realities of working in a lab.

Rules
This is a science community. We use the Dawkins definition of meme.
The colloquial meaning is different from a topological definition. Anything with a through-hole has a hole at each end. It's an ambiguous question because the answer depends whether you're referring to a openings in the face of the object (a cylinder in the case of a straw) or the void connecting the surface openings. Perhaps the safest answer is inclusive, so three. I've been told I'm not fun at parties.
You could make infinite indentations in an object with zero holes. That's a very poor definition for a hope topologically.
Openings and indentations aren't the same thing though, are they?
Correct, a hole is a topological feature.