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Actually I've had a bad case of covid for like 4 days now and haven't been able to breathe out of my nose. While not technically nose drugs, I took one of my wife's Adderall and like magic I'm breathing through my nose again. Still feel terrible and can't sleep now but I'm no longer a mouth breather. I couldn't sleep last night because my mouth would dry out every 5 minutes so bad I'd have to take a drink of water every few minutes then pee.
Amphetamine used to be used exactly for this, its why Sudafed or gtfo when it comes to blocked nose