I let them be.

Spiders are cool in the way that you always have the same mass of spiders in your house.

You either have a lot of small ones or a few big ones. You can disrupt the balance of sizes by killing the big ones or by vacuuming the small ones, but at the end of the week the mass stays the same.

I'd be more worried if I didn't have spiders in my home. That only happens in environments that are also unsuitable for humans.